반응 #656224

반응 방정식

6-amino-β-carboline-4-carboxylic acid ethyl ester

diazabicycloundecane

allylbromide

→

6-diallylamino-β-carboline-4-carboxylic acid ethyl ester

용매

ethanol

반응 조건

후처리

1. 1
   기타Then the solution is evaporated
2. 2
   추출The evaporation residue is extracted with ethyl acetate and water
3. 3
   기타the combined extracts are evaporated
4. 4
   기타chromatographed on silica gel with methylene chloride/methanol=5:1

실험 절차

A solution of 0.28 g of 6-amino-β-carboline-4-carboxylic acid ethyl ester, 0.18 g of diazabicycloundecane and 0.26 g of allylbromide in 5 ml of ethanol is heated for 3 hours to 70° C. Then the solution is evaporated. The evaporation residue is extracted with ethyl acetate and water, the combined extracts are evaporated and chromatographed on silica gel with methylene chloride/methanol=5:1. Yield: 0.05 g.

출처