반응 #65584

반응 방정식

1-(3 phenyl-1-propenyl)cyclododecane

hydrogen

→

1-(3-phenylpropyl)cyclododecane

용매

ethanol

반응 조건

후처리

1. 1
   여과The reaction mixture is filtered through Celite which
2. 2
   세척is washed with additional ethanol
3. 3
   기타The filtrate is evaporated

실험 절차

To 6.4 g (22.5 mmoles) of 1-(3 phenyl-1-propenyl)cyclododecane in 50 mL of ethanol is added 0.48 g of 10% palladium on carbon. The reaction mixture is subjected to hydrogen (50 psi) atmosphere using a Paar hydrogenerator and shaken overnight after which time no starting material is evident by TLC. The reaction mixture is filtered through Celite which is washed with additional ethanol. The filtrate is evaporated and the crude residue (5.8 g) is used directly for the next step: NMR (CDCl3) δ 1.2-1.4 (m, 10H), 1.6 (m, 2H), 2.55 (t, 2H, J=8 Hz), 7.2 (m, 5H).

출처