반응 #65568

반응 방정식

p-xyloquinone

thiourea

hydrochloric acid

→

title compound

2-Amino-6-hydroxy-4,7-dimethylbenzothiazole hydrochloride

용매

ethanol

ethanol

반응 조건

후처리

1. 1
   workup.STIRRINGThe reaction mixture was stirred at room temperature for 24 hours
2. 2
   농축concentrated to about one-half
3. 3
   기타The crystals thus precipitated
4. 4
   기타were separated
5. 5
   여과by filtering
6. 6
   세척washed with a small amount of ethanol

실험 절차

To 2.24 g of thiourea were added 60 ml of ethanol and 2.5 ml of concentrated hydrochloric acid, followed by stirring. Then a solution of 8.0 g of p-xyloquinone in ethanol (120 ml) was slowly added dropwise thereto. The reaction mixture was stirred at room temperature for 24 hours and then concentrated to about one-half. The crystals thus precipitated were separated by filtering and washed with a small amount of ethanol. Thus 6.80 g of the title compound was obtained in the form of white crystals.

출처