반응 #65564

반응 방정식

2-(1-naphthyl)acetonitrile

dimethyl carbonate

sodium

methanol

→

2-(1-naphthyl)-2-(methoxycarbonyl)acetonitrile

반응 조건

후처리

1. 1
   온도the solution is heated to reflux
2. 2
   기타evaporates off
3. 3
   온도The reaction medium is kept refluxing for 1 hour
4. 4
   기타the excess dimethyl carbonate is then evaporated off to dryness

실험 절차

0.1 mol of 2-(1-naphthyl)acetonitrile is dissolved in 120 cm3 of dimethyl carbonate, and the solution is heated to reflux. 0.1 mol of sodium is then added in small portions over 30 min, during which time the methanol evaporates off. The reaction medium is kept refluxing for 1 hour, and the excess dimethyl carbonate is then evaporated off to dryness. The residue is taken up with 100 cm3 of an 18% solution of acetic acid in water.

출처