반응 #65472

반응 방정식

methyl 2-[[3-[4-(5-chloro-2-methoxyphenyl)piperain-1-yl]propyl]amino]-pyrazine-5-carboxylate

1,1-dimethylethyl 2-aminoethylcarbamate

→

1,1-Dimethylethyl 2-[[[2-[[3-[4-(5-chloro-2-methoxyphenyl)piperazin-1-yl]propyl]amino]pyrazin-5-yl]carbonyl]amino]ethylcarbamate

용매

2-propanol

반응 조건

후처리

1. 1
   온도the mixture is heated
2. 2
   온도at reflux for 2 days

실험 절차

4 g (0.0095 mol) of methyl 2-[[3-[4-(5-chloro-2-methoxyphenyl)piperain-1-yl]propyl]amino]-pyrazine-5-carboxylate and 3.05 g (0.02 mol) of 1,1-dimethylethyl 2-aminoethylcarbamate are introduced into 10 ml of 2-propanol in a 0.5 l round-bottomed flask and the mixture is heated at reflux for 2 days.

출처