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6,7-dichloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

1-chloro-3-(1H-indole-4-oxy)propane

potassium carbonate

→

title compound

3-[4-(6,7-dichloro-3-indolyl)-1,2,3,6-tetrahydropyridin-1-yl] 1-(4-indolyloxy)propane

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후처리

1. 1
   기타The product was isolated as a white granular solid

실험 절차

The title compound was prepared in a fashion similar to that described in Example 192 from 6,7-dichloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (0.70 g, 2.6 mmol), 1-chloro-3-(1H-indole-4-oxy)propane (0.60 g, 2.9 mmol) and potassium carbonate (0.48 g, 3.5 mmol). The product was isolated as a white granular solid. Yield 220 mg (19%). mp 224-227° C. FDMS m/e=439 (M+ of free base).

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