반응 #65273

반응 방정식

methyl 3-benzyl-3-(2-thienyl)propanoate

ii

1-(2-chlorophenyl)methyl-5-carboxymethyl-2-propylthio-1H-imidazole

iii

E-3-[1-(2-chlorophenyl)methyl-2-propylthio-1H-imidazol-5-yl]-2-(2-thienyl)methyl-2-propenoic acid

iv

(E)-3-[2-n-butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-(4-pyridyl)-methyl-2-propenoic acid

→

title compound

(E)-3-[2-n-Butyl-1-{(2-chlorophenyl)methyl}-1H-imidazol-5-yl]-2-[2-phenyl-1-(2-thienyl)ethyl]-2-propenoic Acid

반응 조건

후처리

1. 1
   기타prepared

실험 절차

The title compound was prepared using the procedure of Example 1 (i, ii, iii, iv [Method B]) replacing methyl 3-(2-thienyl)propanoate with methyl 3-benzyl-3-(2-thienyl)propanoate [prepared following the procedure described in Tetra. 44 (7) 2055 (1988)]; mp 200°-202° C.

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