반응 #652729

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6-trifluoromethyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

1-chloro-3-(1H-indole-4-oxy)propane

potassium carbonate

→

title compound

3-[4-(6-trifluoromethyl-3-indolyl)-1,2,3,6-tetrahydropyridin-1-yl]-1-(4-indolyloxy)propane

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후처리

1. 1
   기타The product was isolated as a white foam

실험 절차

The title compound was prepared in a fashion similar to that described in Example 192 from 6-trifluoromethyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (0.50 g, 1.9 mmol), 1-chloro-3-(1H-indole-4-oxy)propane (0.39 g, 1.9 mmol) and potassium carbonate (0.29 g, 2.1 mmol). The product was isolated as a white foam. Yield 0.53 g (64%). mp 190-195° C. FDMS m/e=440 (M+ of free base).

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