반응 #65210

반응 방정식

5-hydroxyindan

triethylamine

2-methylbenzoyl chloride

→

5-(2-methylbenzoyloxy)indan

용매

dichloromethane

반응 조건

후처리

1. 1
   온도cooling for one hour
2. 2
   세척after which it was washed with water
3. 3
   건조dried (MgSO4)
4. 4
   workup.DISTILLATIONThe solvent was then distilled off

실험 절차

To an ice-cooled mixture of 5-hydroxyindan (13.4 g), triethylamine (14.0 ml) and dichloromethane (150 ml) was added 2-methylbenzoyl chloride (15.4 ml) dropwise with constant stirring. The mixture was further stirred under ice-cooling for one hour, after which it was washed with water and dried (MgSO4). The solvent was then distilled off to give 5-(2-methylbenzoyloxy)indan as oil in quantitative yield.

출처