반응 #651862

ord-5da2f766f79d4a14b7538a3f80a8f37d

반응 방정식

CCCCCCCCOc1ccc2c(c1)cc(F)c1cc(Br)ccc12
7-bromo-9-fluoro-2-octyloxyphenanthrene
CCCCCCCCOc1ccc(B(O)O)c(F)c1F
2,3-difluoro4-octyloxyphenylboronic acid
O=C([O-])[O-].[Na+].[Na+]
sodium carbonate
→
CCCCCCCCOc1ccc2c(c1)cc(F)c1cc(-c3ccc(OCCCCCCCC)c(F)c3F)ccc12
9-Fluoro-7-(2,3-difluoro4-octyloxyphenyl)-2-octyloxyphenanthrene

반응물

CCCCCCCCOc1ccc2c(c1)cc(F)c1cc(Br)ccc12
7-bromo-9-fluoro-2-octyloxyphenanthrene
CCCCCCCCOc1ccc(B(O)O)c(F)c1F
2,3-difluoro4-octyloxyphenylboronic acid
O=C([O-])[O-].[Na+].[Na+]
sodium carbonate

시약

[Pd].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1
tetrakis(triphenylphosphine)-palladium (0)

용매

CCO.Cc1ccccc1.O
toluene ethanol H2O

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

From 7-bromo-9-fluoro-2-octyloxyphenanthrene by reaction with 2,3-difluoro4-octyloxyphenylboronic acid, sodium carbonate and tetrakis(triphenylphosphine)-palladium (0) in toluene/ethanol/H2O.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US06168838Auspto-grants-2001_01