반응 #64982

반응 방정식

8-benzyl-4-methyl-2,8-diazabicyclo[4.3.0]nonane

→

4-Methyl-2,8-diazabicyclo[4.3.0]nonane

용매

methanol

palladium

charcoal

반응 조건

후처리

1. 1
   여과Then the catalyst is filtered off
2. 2
   농축the filtrate is concentrated by evaporation
3. 3
   workup.DISTILLATIONthe residue is distilled

실험 절차

8.0 g (35 mmol) of 8-benzyl-4-methyl-2,8-diazabicyclo[4.3.0]nonane are dissolved in 60 ml of methanol and hydrogenated over palladium on acitive charcoal at 100° C. and under 100 bar. Then the catalyst is filtered off, the filtrate is concentrated by evaporation and the residue is distilled.

출처