반응 #64972

반응 방정식

7-acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

NaOH

K2CO3

→

1,2-Dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane

용매

water

반응 조건

후처리

1. 1
   추출extracted several times with CHCl3
2. 2
   건조the extract is dried over K2CO3
3. 3
   농축concentrated
4. 4
   workup.DISTILLATIONthe residue is distilled

실험 절차

11.8 g (64mmol) of 7-acetyl-1,2-dimethyl-3-oxa-2,7-diazabicyclo[3.3.0]octane are heated under reflux with 12 g of NaOH in 36 ml of water overnight. The mixture is saturated with K2CO3 and extracted several times with CHCl3, the extract is dried over K2CO3 and concentrated and the residue is distilled.

출처