반응 #64950

반응 방정식

6-benzyl-octahydropyrrolo[3,4-b]pyridine

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Octahydropyrrolo[3,4-b]pyridine

용매

methanol

반응 조건

후처리

1. 1
   기타in the course of 3 hours
2. 2
   여과The catalyst is then filtered off
3. 3
   농축the filtrate is concentrated
4. 4
   workup.DISTILLATIONthe residue is distilled
5. 5
   기타a boiling point of 78° C./9 mbar are obtained

실험 절차

69 g (0.32 mol) of 6-benzyl-octahydropyrrolo[3,4-b]pyridine are hydrogenated in 450 ml of methanol over 7 g of palladium-on-active charcoal (5% strength) at 90° C./90 bar in the course of 3 hours. The catalyst is then filtered off, the filtrate is concentrated and the residue is distilled. 33.8 g (84.% of theory) of a colorless solid having a melting point of 65°-67° C. and a boiling point of 78° C./9 mbar are obtained.

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