반응 #64769
ord-76c44d27eb4b427882d1bb80398ab9ef
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1추출extracted with a 1:1 ether
- 2세척The combined organic extracts were washed (water, brine)
- 3건조dried (Na2SO4)
- 4여과filtered
- 5기타evaporated
실험 절차
A mixture of ethyl p-hydroxybenzoate (4.98 g), benzyl bromoacetate (4.75 ml) and K2CO3 (4.14 g) was stirred for 15 hr in 30 ml of DMF. The reaction mixture was diluted with water (200 ml) and extracted with a 1:1 ether:hexane mixture. The combined organic extracts were washed (water, brine), dried (Na2SO4), filtered, and evaporated leaving 9.3 g, (99%) of the title compound as a heavy oil; TLC, Rf =0.71, Et2O: hexane (1:1).