반응 #64755

반응 방정식

propylene glycol methyl ether

cyclohexene oxide

PM

→

2-hydroxycyclohexyloxymethoxypropane

수율 27.4%

반응 조건

후처리

1. 1
   기타equipped with a reflux tube
2. 2
   온도under reflux at a temperature for a reflux reaction for 10 hours
3. 3
   기타Results of the analysis of the resultant
4. 4
   기타reaction mixture by GC
5. 5
   기타Then, the obtained reaction mixture
6. 6
   workup.DISTILLATIONwas subjected to distillation

실험 절차

45 g (0.5 mole) of propylene glycol methyl ether (PM), 33 g (0.33 mole) of cyclohexene oxide and 0.3 g (0.007 mole) of sodium hydroxide were charged in a 100 ml eggplant type flask equipped with a reflux tube, and a reaction was allowed to proceed under reflux at a temperature for a reflux reaction for 10 hours. Results of the analysis of the resultant reaction mixture by GC showed that the conversion of PM was 20%. Then, the obtained reaction mixture was subjected to distillation, to thereby obtain 17 g of 2-hydroxycyclohexyloxymethoxypropane, i.e., propylene glycol methyl 2-hydroxycyclohexyl ether (hereinafter referred to as "PGMHCHE"). The IR spectrum of the product is shown in FIG. 3. Other properties of the product were measured and results are shown in Table 1.

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