반응 #64696

반응 방정식

Meldrum's acid

formic acid

triethylamine

veratraldehyde

→

3-(3,4-dimethoxyphenyl)propionic acid

용매

dimethylformamide

반응 조건

후처리

1. 1
   기타prepared
2. 2
   workup.ADDITIONwere added to the above mixture, which
3. 3
   기타reacted at the same temperature for 3 hours
4. 4
   기타The product was separated from the reaction mixture by the method

실험 절차

After adding 6.25 ml of the mixture of formic acid and triethylamine prepared as described in Example 1 to 15 ml of dimethylformamide, 3.60 g (0.025 mol) of Meldrum's acid and 4.15 g (0.025 mol) of veratraldehyde were added to the above mixture, which was then heated to 110° C. during 1 hour and reacted at the same temperature for 3 hours. The product was separated from the reaction mixture by the method as described in Example 1.

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