반응 #64682

반응 방정식

Tetra(n-butyl)ammonium hydroxide

thymine

→

tetra (n-butyl) ammonium

thymine

용매

dimethylformamide

반응 조건

후처리

1. 1
   기타the dimethylformamide was removed in vacuo
2. 2
   workup.ADDITIONAdditional dimethylformamide (20 ml.) was added to the white residue
3. 3
   기타removed in vacuo
4. 4
   기타the residue was dried under a vacuum (0.1 mm) at 50° C. overnight

실험 절차

1.5M Tetra(n-butyl)ammonium hydroxide (4.22 ml., 6.335 mmole) was added to a suspension of thymine (0.913 g., 7.24 mmole) in dimethylformamide (15 ml.). The mixture was stirred for 10 minutes, and the dimethylformamide was removed in vacuo. Additional dimethylformamide (20 ml.) was added to the white residue, and removed in vacuo. This process was repeated four times and the residue was dried under a vacuum (0.1 mm) at 50° C. overnight affording the tetra (n-butyl) ammonium salt of thymine.

출처