반응 #64669

반응 방정식

tetrahydrofuran N-(13-benzyloxycarbonyltridecanoyloxy)succinimide

→

N-(13-carboxytridecanoyloxy)succinimide

수율 94.0%

반응 조건

후처리

1. 1
   여과The reaction mixture was filtered
2. 2
   농축the filtrate was concentrated under reduced pressure
3. 3
   기타The residue was recrystallized from ethanol

실험 절차

In 15 ml of tetrahydrofuran N-(13-benzyloxycarbonyltridecanoyloxy)succinimide (2.28 g, 5.12 mmoles) was dissolved. To the obtained solution, were added 228 mg of 10% palladium carbon and the mixture was stirred for 15 hours under an atmosphere of hydrogen. The reaction mixture was filtered and the filtrate was concentrated under reduced pressure. The residue was recrystallized from ethanol, to give N-(13-carboxytridecanoyloxy)succinimide (1.71 mg, 94%) having the following properties.

출처