반응 #64604

반응 방정식

Tetra(n-butyl)ammonium hydroxide

thymine

→

tetra(n-butyl)ammonium

thymine

용매

dimethylformamide

반응 조건

후처리

1. 1
   기타the dimethylformamide was removed in vacuo
2. 2
   workup.ADDITIONAdditional dimethylformamide (20 ml. ) was added to the white residue
3. 3
   기타removed in vacuo
4. 4
   기타the residue was dried under a vacuum (0.1 mm) at 50° C. overnight

실험 절차

1.5M Tetra(n-butyl)ammonium hydroxide (4.22 ml., 6.335 mole) was added to a suspension of thymine (0.913 g., 7.24 mole) in dimethylformamide (15 ml. ). The mixture was stirred for 10 minutes, and the dimethylformamide was removed in vacuo. Additional dimethylformamide (20 ml. ) was added to the white residue, and removed in vacuo. This process was repeated four times and the residue was dried under a vacuum (0.1 mm) at 50° C. overnight affording the tetra(n-butyl)ammonium salt of thymine.

출처