반응 #64603

반응 방정식

6-iodo-2-aminopurine

tetra(n-butyl)ammonium hydroxide

→

tetra(n-butyl)ammonium

6-iodo-2-aminopurine

용매

methylene chloride

반응 조건

후처리

1. 1
   기타the volatiles were removed in vacuo
2. 2
   workup.ADDITIONMethylene chloride (12 ml.) was added to the white residue
3. 3
   건조the resulting solution was dried (magnesium sulfate)
4. 4
   여과filtered
5. 5
   농축the filtrate was concentrated in vacuo

실험 절차

To a mixture of 6-iodo-2-aminopurine (1.21 g., 4.637 mmole) in methylene chloride (12 ml.) at room temperature, was added 1.5M tetra(n-butyl)ammonium hydroxide (2.7 ml., 4.05 mmole). The reaction mixture was stirred for 10 minutes, and the volatiles were removed in vacuo. Methylene chloride (12 ml.) was added to the white residue, and the resulting solution was dried (magnesium sulfate), filtered, and the filtrate was concentrated in vacuo to yield the tetra(n-butyl)ammonium salt of 6-iodo-2-aminopurine as a white residue.

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