반응 #64356

반응 방정식

N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide

ethyl iodide

hydride

tetrahydrofuran

Dichloromethane

→

N-ethyl-N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide

반응 조건

후처리

1. 1
   온도was heated
2. 2
   온도at reflux for 30 minutes
3. 3
   기타any insoluble matter was removed by filtration
4. 4
   기타The filtrate was recrystallized from a mixture of diethyl ether and n-hexane

실험 절차

A mixture of 0.53 g of N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide, 1.60 g of ethyl iodide, 0.09 g of sodlum hydride, and 10 ml of tetrahydrofuran was heated at reflux for 30 minutes. Dichloromethane was added to the reaction mixture, and any insoluble matter was removed by filtration. The filtrate was recrystallized from a mixture of diethyl ether and n-hexane to obtain 0.45 g of N-ethyl-N-methyl-6-nitro-2,2-dimethyl-2H-1-benzopyran-4-carboxamide represented by formula shown below.

출처