반응 #64242

ord-ecd17fce5fe54de281b5939c329ed015

반응 방정식

N#CCC(=O)N[C@H]1CC[C@H](O[N+](=O)[O-])CC1
2-cyano-N-(trans-4-nitroxycyclohexyl)-acetic acid amide
N#CCC(=O)N[C@H]1CC[C@H](O)CC1
2-cyano-N-(trans-4-hydroxycyclohexyl)-acetic acid amide
→
CC(=O)N[C@H]1CC[C@H](O[N+](=O)[O-])CC1
trans-N-acetyl-4-nitroxycyclohexylamine
수율 53.0%

반응물

N#CCC(=O)N[C@H]1CC[C@H](O[N+](=O)[O-])CC1
2-cyano-N-(trans-4-nitroxycyclohexyl)-acetic acid amide
N#CCC(=O)N[C@H]1CC[C@H](O)CC1
2-cyano-N-(trans-4-hydroxycyclohexyl)-acetic acid amide

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

2-cyano-N-(trans-4-nitroxycyclohexyl)-acetic acid amide from 2-cyano-N-(trans-4-hydroxycyclohexyl)-acetic acid amide melting point: 149°-150° C. (ether), yield: 53% of theory.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US05411989uspto-grants-1995_05