반응 #6417

반응 방정식

sodium hydroxide

8-bromo-1-octene

ethyl p-hydroxybenzoate

potassium carbonate

hydrochloric acid

→

p-(7-octenyloxy)benzoic acid

수율 89.0%

용매

water

ethanol

반응 조건

후처리

1. 1
   workup.ADDITIONAdded
2. 2
   온도reflux
3. 3
   기타After conclusion of the reaction
4. 4
   기타The generated precipitate was collected
5. 5
   세척was then washed with water sufficiently
6. 6
   기타dried
7. 7
   기타to obtain 10.8 g of the objective ether compound

실험 절차

9.4 g of 8-bromo-1-octene, 9.0 g of ethyl p-hydroxybenzoate, and 7.6 g of potassium carbonate were refluxed in ethanol for 10 hours. Added thereto was an aqueous solution containing 2.4 g of sodium hydroxide, and reflux was further continued for 10 hours. After conclusion of the reaction, the reaction solution was diluted with water, and the pH of the diluted solution was lowered to 2 by dropping hydrochloric acid thereto. The generated precipitate was collected, and was then washed with water sufficiently and dried, to obtain 10.8 g of the objective ether compound. (Yield: 89%)

출처