반응 #640589

반응 방정식

cyanogen bromide

(±)-trans-1,2-cyclohexanediamine

3,4-difluorobenzaldehyde

→

title compound

(±)-trans-1,3-Bis-(3,4-difluoro-benzyl)octahydro-benzoimidazol-2-ylideneamine

반응 조건

후처리

1. 1
   기타the reaction mixture was evaporated to dryness
2. 2
   세척the crude product washed with ether
3. 3
   기타recrystallized from MeOH

실험 절차

The title compound was prepared from (±)-trans-1,2-cyclohexanediamine and 3,4-difluorobenzaldehyde by Procedure C. After reacting with cyanogen bromide, the reaction mixture was evaporated to dryness and the crude product washed with ether and recrystallized from MeOH to give the title compound as the hydrogen bromide salt (mp 238-240° C.). MS (ES+) m/z 392 ([M+1]+, 100).

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