반응 #63975

반응 방정식

formamide

N-formyl-1-[1-(3,4-dichlorophenyl)cyclobutyl]ethylamine

→

hydrochloric acid

1-[1-(3,4-dichlorophenyl)cyclobutyl]ethylamine

용매

반응 조건

후처리

1. 1
   기타the product isolated
2. 2
   온도by cooling the reaction mixture
3. 3
   기타collecting the solid
4. 4
   기타produced by filtration

실험 절차

The preparation of N-formyl-1-[1-(3,4-dichlorophenyl)cyclobutyl]ethylamine (m.p. 124°-125° C.) (Example 1(a) Formula I R1 =Me; R2 =H; R3 =H; R4 =CHO; R5 =4--Cl and R6 =3--Cl) described above was repeated and the product isolated by cooling the reaction mixture and collecting the solid produced by filtration. The formamide was then hydrolysed by concentrated hydrochloric acid in industrial methylated spirit to give the hydrochloride salt of 1-[1-(3,4-dichlorophenyl)cyclobutyl]ethylamine.

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