반응 #639730

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4-(3,5-Difluoro-phenyl)-6-methyl-pyridine-2-carboxylic acid ethyl ester

5-Fluoro-thiazol-2-ylamine

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title compound

4-(3,5-Difluoro-phenyl)-6-methyl-pyridine-2-carboxylic acid (5-fluoro-thiazol-2-yl)-amide

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실험 절차

The title compound, was prepared from 4-(3,5-Difluoro-phenyl)-6-methyl-pyridine-2-carboxylic acid ethyl ester in accordance with the general method of example 26, step 6 using 5-Fluoro-thiazol-2-ylamine (CAS: [64588-82-5], WO2006016178 instead of 3-Chloroaniline to yield the final compound as a light yellow crystalline solid, MS (ISP): m/e=350.2 (M+H)+.

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