반응 #63712

반응 방정식

o-cresol

butanethiol

o-cresol

chlorotrimethyl silane

1,2-dichloroethane

cyclohexanone

→

1,1-Bis(3-methyl-4-hydroxyphenyl)cyclohexane

수율 76.0%

용매

methylene chloride

cyclohexane

반응 조건

후처리

1. 1
   여과by filtering it
2. 2
   기타hot after the reaction
3. 3
   여과filtering
4. 4
   세척washing several times with methylene chloride
5. 5
   기타There was obtained the cyclohexane product in a 76 percent yield
6. 6
   기타after drying in vacuo at 80° C. for 12 hours

실험 절차

The preparation of the above cyclohexane was accomplished by repeating the procedure of Example I with the exception that o-cresol was employed in place of phenol. In addition, the preparation was affected in a 250-milliliter 3-necked round-bottomed flask with 0.2 mole of cyclohexanone, and without 1,2-dichloroethane as a solvent. Additionally, 108 grams of o-cresol, 22 grams of chlorotrimethyl silane, and 0.1 gram of butanethiol were employed. The reaction mixture was worked up by filtering it hot after the reaction, followed by slurrying up the filter cake in methylene chloride, filtering and washing several times with methylene chloride. There was obtained the cyclohexane product in a 76 percent yield after drying in vacuo at 80° C. for 12 hours, which product had a melting point of 190° to 191° C.

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