반응 #63429

반응 방정식

arecoline HBr

KOH

NaCl

→

Arecoline

용매

water

—

petroleum ether

반응 조건

후처리

1. 1
   workup.ADDITIONthe layers were mixed
2. 2
   농축to saturate the aqueous layer
3. 3
   기타The organic layer was collected
4. 4
   추출the aqueous layer was extracted three more times with petroleum ether
5. 5
   기타The combined organic layers were transferred to a 500 ml round bottom flask
6. 6
   workup.ADDITIONwere added
7. 7
   기타the petroleum ether was removed by distillation

실험 절차

Ten grams of arecoline HBr was dissolved in a minimal quantity (approximately 25 ml) of water and adjusted to pH 10 with saturated KOH in a separatory funnel. One hundred mls of petroleum ether was added and the layers were mixed. NaCl was then added to saturate the aqueous layer. The organic layer was collected, and the aqueous layer was extracted three more times with petroleum ether. The combined organic layers were transferred to a 500 ml round bottom flask, boiling chips were added and the petroleum ether was removed by distillation. The remaining oil was layered with N2 and stored in low-actinic glassware. The oil was anlyzed by NMR to show the absence of a halogen component.

출처