반응 #63314

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3-[3-(1,3,-Dioxolan-2-yl)phenoxy]propanamine

N-cyano-1-methyl-2-(phenylmethylene)hydrazinecarboximidothioic acid methyl ester

→

title compound

N'-Cyano-N-[3-[3-(1,3-dioxolan-2-yl)phenoxy]propyl]-1-methyl-2-(phenylmethylene)hydrazinecarboximidamide

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실험 절차

3-[3-(1,3,-Dioxolan-2-yl)phenoxy]propanamine (8.92 g) and N-cyano-1-methyl-2-(phenylmethylene)hydrazinecarboximidothioic acid methyl ester (9.28 g) were heated under water-pump vacuum at 80° for 4 h to yield the title compound, a pale yellow glass (16.03 g). TLC silica; ethyl acetate:cyclohexane 1:1; Rf 0.2 NMR (CDCl3) 2.3-2.2 m (10H); 4.36 s (1H), 5.8-6.1 m (8H); 6.55 s (3H); 7.83 m (2H).

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