반응 #63217

반응 방정식

t-butyl [2-(3-methyl-4-nitropyridine-2-carboxamido)ethyl]carbamate

trifluoroacetic acid

hydrochloride

→

N-(2-aminoethyl)-3-methyl-4-nitropyridine-2-carboxamide hydrochloride

반응 조건

후처리

1. 1
   기타was recrystallized from methanol/ether

실험 절차

14.6 g of t-butyl [2-(3-methyl-4-nitropyridine-2-carboxamido)ethyl]carbamate were reacted with trifluoroacetic acid in an analogous manner to that described in Example 2, paragraph 2. The residue was converted into the hydrochloride which was recrystallized from methanol/ether, whereby there was obtained N-(2-aminoethyl)-3-methyl-4-nitropyridine-2-carboxamide hydrochloride as white crystals, m.p. 204°-205°.

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