반응 #632108

반응 방정식

5-bromothiophene-2-carboxylic acid

3-amino-N-cyclopropyl-4-methylbenzamide hydrochloride

→

5-Bromo-N-(5-(cyclopropylcarbamoyl)-2-methylphenyl)thiophene-2-carboxamide

반응 조건

후처리

1. 1
   기타Compound a was prepared
2. 2
   기타HPLC Ret time=3.16 min

실험 절차

Compound a was prepared by coupling 5-bromothiophene-2-carboxylic acid with 3-amino-N-cyclopropyl-4-methylbenzamide hydrochloride (prepared as described in WO04071440) using the method described in Example 2. HPLC Ret time=3.16 min. LCMS [M+H]+ 379.15.

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