반응 #63154

반응 방정식

product

2-(4,5-Dihydro-4-methyl-5-oxo-1,3,4-oxadiazol-2-yl)benzenesulfonamide

phenyl(4-methyl-6-methoxy-1,3,5-triazin-2-yl)carbamate

DBU

→

subject compound

수율 45.2%

4,5-Dihydro-4-methyl-5-oxo-1,3,4-oxadiazol-2-yl-N[(4-methyl-6-methoxy-1,3,5-triazin-2-yl)aminocarbonyl]benzenesulfonamide

수율 45.2%

용매

p-dioxane

반응 조건

후처리

1. 1
   기타The isolated crude solid
2. 2
   기타was purified
3. 3
   세척by slurry-washing with 10 ml of warm acetonitrile

실험 절차

By the procedure of Example 5, 0.4 g of the product of Example 4 was reacted with 0.41 g of phenyl(4-methyl-6-methoxy-1,3,5-triazin-2-yl)carbamate and 0.24 g of "DBU" in 10 ml of p-dioxane. The isolated crude solid was purified by slurry-washing with 10 ml of warm acetonitrile to yield 0.3 g of the subject compound; m.p. 198°-200° C.

출처