반응 #6296

반응 방정식

4-fluorobenzaldehyde

N-butyl-N-4-hydroxybutylamine

potassium carbonate

→

4-(N-4-hydroxybutyl-N-butylamino)benzaldehyde

용매

dimethylsulfoxide

반응 조건

후처리

1. 1
   기타To a three neck flask fitted with a mechanical stirrer
2. 2
   온도After cooling to room temperature
3. 3
   여과the solid product is collected by filtration
4. 4
   기타purified by recrystallization from tetrahydrofuran/benzene

실험 절차

To a three neck flask fitted with a mechanical stirrer, a thermometer, and a condenser, is added 124 g (1 mole) of 4-fluorobenzaldehyde, 145.3 g (1 mole) of N-butyl-N-4-hydroxybutylamine, 138.2 g (1 mole) of anhydrous potassium carbonate, and dimethylsulfoxide. The mixture is then heated at 95° C. until the reaction is complete. After cooling to room temperature, the solution is poured into a four-fold excess of ice water, and the solid product is collected by filtration and purified by recrystallization from tetrahydrofuran/benzene.

출처