반응 #6295

반응 방정식

4-(N-2-hydroxyethyl-N-ethylamino)cinnamaldehyde

aniline

toluenesulfonic acid

methacrylic acid

4-nitrophenylacetic acid

→

4-(N-2-hydroxyethyl-N-ethylamino)-4'-nitro-1,4-diphenyl-1,3-butadiene

용매

water

toluene

반응 조건

후처리

1. 1
   온도The mixture then is heated
2. 2
   온도at reflux for 16 hours
3. 3
   온도After cooling to room temperature
4. 4
   기타the solid diphenylbutadiene precipitates from solution
5. 5
   여과is collected by filtration
6. 6
   기타purified by recrystallization from ethanol

실험 절차

A solution of 21.9 g (0.1 mole) of 4-(N-2-hydroxyethyl-N-ethylamino)cinnamaldehyde, 9.3 g (1 mole) of aniline, and 0.19 g (1 mole %) of toluenesulfonic acid in toluene is heated at reflux for 17 hours with azeotropic removal of water. After the mixture is cooled to room temperature, 17.2 g (0.2 mole) of methacrylic acid and 18.1 g (0.1 mole) of 4-nitrophenylacetic acid are added to the solution, and the reaction is stirred at room temperature for 3 hours. The mixture then is heated at reflux for 16 hours. After cooling to room temperature, the solid diphenylbutadiene precipitates from solution and is collected by filtration and purified by recrystallization from ethanol.

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