반응 #6287

반응 방정식

4-hydroxymethyl-2-methoxy-2-phenyl-1,3-dioxolane

triethylamine

acryloyl chloride

→

4-acryloyloxymethyl-2-methoxy-2-phenyl-1,3-dioxolane

용매

methylene chloride

반응 조건

후처리

1. 1
   기타The crude product was purified by column chromatography over basic alumina

실험 절차

The procedure of Example A was repeated, employing 21 grams (100 mmol.) of 4-hydroxymethyl-2-methoxy-2-phenyl-1,3-dioxolane, 25.3 grams (250 mmol.) of triethylamine, 9.5 grams (105 mmol.) of acryloyl chloride and 150 ml. of methylene chloride. The crude product was purified by column chromatography over basic alumina, using 15% (by volume) ethyl acetate in hexane as an eluant, to yield the desired 4-acryloyloxymethyl-2-methoxy-2-phenyl-1,3-dioxolane.

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