반응 #62816

반응 방정식

1-methylcyclohexyl 2-(p-nitrophenyl)-propionate

hydrogen

→

1-methylcyclohexyl 2-(p-aminophenyl)-propionate

수율 67.1%

용매

—

petroleum ether

ethanol

반응 조건

후처리

1. 1
   여과the catalyst was filtered off through celite
2. 2
   기타the filtrate was evaporated to dryness

실험 절차

A stirred solution of 34.9 g of 1-methylcyclohexyl 2-(p-nitrophenyl)-propionate in 250 ml of absolute ethanol was hydrogenated at atmospheric pressure in the presence of 10% palladium on carbon catalyst. After the uptake of hydrogen gas was complete, the catalyst was filtered off through celite and the filtrate was evaporated to dryness. Trituration of the residue with petroleum ether gave 21.02 g (67% yield) of 1-methylcyclohexyl 2-(p-aminophenyl)-propionate as creamy white crystals melting at 85°-87° C.

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