반응 #62797

반응 방정식

thionyl chloride

propionic acid

2,2-bis-acetoxymethyl propionic acid

→

2,2-bis-acetoxymethyl propionic acid chloride

반응 조건

후처리

1. 1
   workup.DISTILLATIONExcess thionyl chloride is distilled off in a water jet vacuum
2. 2
   기타leaving a pale yellow, oily product

실험 절차

182 ml (2.5 moles) of thionyl chloride are poured over 218 g (1 mole) of 2,2-bis-acetonxymethyl propionic acid (step 1), followed by refluxing for 8 hours at a batch temperature of approximately 100° C. Excess thionyl chloride is distilled off in a water jet vacuum, leaving a pale yellow, oily product. Yield 236 g (100% of the theoretical).

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