반응 #62602

반응 방정식

Sodium

3-aminothiophenol

4-methoxybenzyl chloride

→

title compound

3-(((4-Methoxyphenyl)methyl)thio)aniline

용매

DMF

acetonitrile

반응 조건

후처리

1. 1
   여과the resulting solid was collected by filtration
2. 2
   기타dried in air

실험 절차

Sodium ydride (99%, 8.22 g) was added in portions of a stirred solution of 3-aminothiophenol (44.23 g) in dry DMF (132 ml) at 0° . After 30 minutes a solution of 4-methoxybenzyl chloride (53.61 g) in acetonitrile (132 ml) was added dropwise and the mixture was stirred 30 minutes at 0° and 1 hour more at ambient temperature. The mixture was poured into ice-water (200 ml) and the resulting solid was collected by filtration and dried in air to provide the title compound, m.p. 85°-86°.

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