반응 #62504

반응 방정식

6-chloro-4-[1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazoline

pentafluorophenyl-tetramethyluronium hexafluorophosphate

diisopropylethylamine

thiomorpholine

→

6-chloro-4-[1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-(thiomorpholin-4-yl-carbonyl)-quinazoline

용매

DMSO

반응 조건

실험 절차

Prepared analogously to Example 37a from 6-chloro-4-[1-(5-chloro-1H-benzimidazol-2-yl)-ethylamino]-7-hydroxycarbonyl-quinazoline, pentafluorophenyl-tetramethyluronium-hexafluorophosphate (PFTU), diisopropylethylamine and thiomorpholine in DMSO at ambient temperature.

출처