반응 #62404

반응 방정식

acetic anhydride

4-bromo-5-fluoro-2-methylphenylamine

→

title compound

N-(4-Bromo-5-fluoro-2-methylphenyl)acetamide

반응 조건

후처리

1. 1
   workup.DISTILLATIONExcess acetic anhydride was distilled off under reduced pressure
2. 2
   세척the precipitated crystals were washed with water

실험 절차

73.6 mL of acetic anhydride was added with 80.0 g of 4-bromo-5-fluoro-2-methylphenylamine at room temperature, and stirred at this temperature for 10 minutes. Excess acetic anhydride was distilled off under reduced pressure, and the precipitated crystals were washed with water, to afford 77.6 g of the title compound as colorless crystal.

출처