반응 #62307
ord-01a90d08fb0a473ea7da21d086405516
반응 방정식
7-fluoro-3-[(E)-2-(pyridin-3-yl)-vinyl]-1H-indazol-5-ylamine
2-furancarboxylic acid
→
title compound
수율 37.9%
Furan-2-carboxylic acid{7-fluoro-1-(furan-2-carbonyl)-3-[(E)-2-(pyridin-3-yl)-vinyl]-1H-indazole-5-yl}-amide
수율 37.9%
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타with the method of Example 127, purification by LC-MS
실험 절차
Following amidation using 217 mg of 7-fluoro-3-[(E)-2-(pyridin-3-yl)-vinyl]-1H-indazol-5-ylamine and 286 mg of 2-furancarboxylic acid in accordance with the method of Example 127, purification by LC-MS was carried out, to afford 143 mg of the title compound as yellow crystals.