반응 #621325

반응 방정식

6-bromoindolinone

Chlorosulphonic acid

→

6-Bromindolinone-5-sulphonyl chloride

반응 조건

후처리

1. 1
   온도cooled
2. 2
   기타The ice bath is removed
3. 3
   workup.ADDITIONThe reaction mixture is slowly poured onto ice with vigorous stirring
4. 4
   기타the precipitate formed
5. 5
   여과is filtered off
6. 6
   기타dried in the vacuum dryer

실험 절차

Chlorosulphonic acid (30 mL) is taken, cooled to 0° C. cooled and combined with 8 g of 6-bromoindolinone with vigorous stirring. The ice bath is removed and the mixture is stirred for a further 16 h at RT. The reaction mixture is slowly poured onto ice with vigorous stirring, the precipitate formed is filtered off and dried in the vacuum dryer. 6-Bromindolinone-5-sulphonyl chloride is obtained as crude product, which is further used directly.

출처