반응 #6208

반응 방정식

4-(3-aminopropylthio)pyridine

phthalic acid

→

desired compound

수율 92.3%

4-[3-(2-carboxybenzoylamino)propylthio]pyridine

수율 92.3%

용매

methylene chloride

반응 조건

후처리

1. 1
   여과The resulting crystals were filtered
2. 2
   기타dried

실험 절차

A solution of 340 mg (2.02 mmol) of 4-(3-aminopropylthio)pyridine and 738 mg (4.98 mmol) of anhydrous phthalic acid in 5 ml of methylene chloride was stirred at room temperature for 30 minutes. The resulting crystals were filtered and dried to obtain 590 mg of the desired compound (92.3%, colorless powder), mp: 151.0°-153.3° C.

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