반응 #620677

반응 방정식

2-bromomethylthioxanthone

triethanol amine

→

white solids

N-(9-oxo-9H-thioxanthene-2-yl)methyl-N,N,N-tris(2-hydroxyethyl)ammonium bromide

용매

dichloromethane

반응 조건

후처리

1. 1
   workup.ADDITIONafter the addition)
2. 2
   기타the organic solvent was evaporated under reduced pressure

실험 절차

The intermediate (C122-2-2) (2-bromomethylthioxanthone) (1.0 part) was dissolved in dichloromethane (85 g), and triethanol amine [product of Wako Pure Chemical industries, Ltd.] (0.5 parts) was added dropwise to this solution (an exotherm was observed after the addition). The resulting mixture was stirred at room temperature (about 25° C.) for one hour, and the organic solvent was evaporated under reduced pressure. As a result, 2.2 g of white solids were obtained. The white solids were recrystallized in a tetrahydrofuran/dichloromethane mixed solution, and 1.0 part of an intermediate (C122-2-3) was obtained (as brown solids).

출처