반응 #62011

반응 방정식

1-Indanone

p-tolylhydrazine hydrochloride

HCl

→

Indeno[1,2-b]indole

용매

EtOH

반응 조건

후처리

1. 1
   온도the mixture is heated
2. 2
   온도to reflux for 90 min
3. 3
   온도The mixture is cooled
4. 4
   여과filtered
5. 5
   세척the solid is washed with EtOH (600 mL)
6. 6
   기타The off-white solid is dried under vacuum (36.5 g, 72%)

실험 절차

1-Indanone (30.6 g, 232 mmol), p-tolylhydrazine hydrochloride (37.0 g, 233 mmol) in EtOH (350 mL), and aqueous HCl (12 N, 18 mL) are mixed and the mixture is heated to reflux for 90 min. The mixture is cooled and filtered, and the solid is washed with EtOH (600 mL) and then by 20% aqueous EtOH (400 mL), and finally by hexane (200 mL). The off-white solid is dried under vacuum (36.5 g, 72%).

출처