반응 #61972

반응 방정식

4-hydroxybenzaldehyde

1-bromo-3-chloropropane

potassium carbonate

→

title compound

4-(3-Chloro-propoxy)-benzaldehyde

용매

acetone

반응 조건

후처리

1. 1
   온도was heated
2. 2
   온도to reflux for 16 h
3. 3
   여과The resulting mixture was filtered
4. 4
   기타the filtrate was evaporated
5. 5
   workup.DISTILLATIONDistillation of the residue (0.5 mm Hg, 220° C.)

실험 절차

A suspension of 4-hydroxybenzaldehyde (40 g), 1-bromo-3-chloropropane (63 mL), and potassium carbonate (136 g) in acetone (920 mL) was heated to reflux for 16 h. The resulting mixture was filtered, and the filtrate was evaporated. Distillation of the residue (0.5 mm Hg, 220° C.) gave the title compound as a pale yellow oil that crystallized on standing (46 g).

출처