반응 #61970

반응 방정식

4-iodophenol

1-bromo-3-chloropropane

potassium carbonate

→

title compound

1-(3-Chloro-propoxy)-4-iodo-benzene

용매

acetone

반응 조건

후처리

1. 1
   온도was heated
2. 2
   온도at reflux for 16 h
3. 3
   여과The suspension was filtered
4. 4
   기타the filtrate was evaporated in vacuo
5. 5
   workup.DISTILLATIONKugelrohr distillation of the residue (5-10 mm Hg, 210° C.)

실험 절차

A suspension of 4-iodophenol (20 g), 1-bromo-3-chloropropane (18 mL), and potassium carbonate (38 g) in acetone (250 mL) was heated at reflux for 16 h and allowed to cool to room temperature. The suspension was filtered, and the filtrate was evaporated in vacuo. Kugelrohr distillation of the residue (5-10 mm Hg, 210° C.) gave the title compound as a white crystalline solid (22 g).

출처