반응 #619146

반응 방정식

1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea

glycine methyl ester hydrochloride

sodium triacetoxyborohydride

→

desired product

수율 39.0%

{[2-(3,3-Dicyclohexyl-ureido)-thiazol-5-ylmethyl]-amino}-acetic acid methyl ester

수율 39.0%

반응 조건

후처리

1. 1
   기타Prepared

실험 절차

Prepared as described in general procedure (P) using 1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea (31 mg, 0.095 mmol), glycine methyl ester hydrochloride (24 mg, 0.20 mmol) and sodium triacetoxyborohydride (61 mg, 0.286 mmol) to afford 15 mg (39%) of the desired product after purification.

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