반응 #619127

ord-1fd9fffeb5f94f049d67bea655e8247c

반응 방정식

N#CSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea
O[C@H](CS)[C@@H](O)CS
dithioerythritol
ClCCN1CCCCC1
1-(2-chloroethyl)-piperidine
→
O=C(Nc1ncc(SCCN2CCCCC2)s1)N(C1CCCCC1)C1CCCCC1
1,1-Dicyclohexyl-3-[5-(2-piperidin-1-yl-ethylsulfanyl)-thiazol-2-yl]-urea

반응물

N#CSc1cnc(NC(=O)N(C2CCCCC2)C2CCCCC2)s1
1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea
O[C@H](CS)[C@@H](O)CS
dithioerythritol
ClCCN1CCCCC1
1-(2-chloroethyl)-piperidine

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타Prepared

실험 절차

Prepared as described in general procedure (II) using 1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and 1-(2-chloroethyl)-piperidine

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: USRE045183E1uspto-grants-2014_10