반응 #619101

ord-16d2be32c60a40f497c0574abdd22682

반응 방정식

CC1CCC(N(C(=O)Nc2ncc(Br)s2)C2CCCC2)CC1
3-(5-bromo-thiazol-2-yl)-1-cyclopentyl-1-(4-methyl-cyclohexyl)-urea
CC1CCC(N(C(=O)Nc2ncc(Br)s2)C2CCCC2)CC1
3-(5-Bromo-thiazol-2-yl)-1-cyclopentyl-1-(4-methyl-cyclohexyl)-urea
COC(=O)CCS
3-mercaptopropionic acid methyl ester
→
COC(=O)CCSc1cnc(NC(=O)N(C2CCCC2)C2CCC(C)CC2)s1
3-{2-[3-Cyclopentyl-3-(4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-propionic acid methyl ester

반응물

CC1CCC(N(C(=O)Nc2ncc(Br)s2)C2CCCC2)CC1
3-(5-bromo-thiazol-2-yl)-1-cyclopentyl-1-(4-methyl-cyclohexyl)-urea
CC1CCC(N(C(=O)Nc2ncc(Br)s2)C2CCCC2)CC1
3-(5-Bromo-thiazol-2-yl)-1-cyclopentyl-1-(4-methyl-cyclohexyl)-urea
COC(=O)CCS
3-mercaptopropionic acid methyl ester

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

후처리

  1. 1
    기타Prepared

실험 절차

Prepared as described in general procedure (D) using 3-(5-bromo-thiazol-2-yl)-1-cyclopentyl-1-(4-methyl-cyclohexyl)-urea (Example 202) and 3-mercaptopropionic acid methyl ester.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: USRE045183E1uspto-grants-2014_10